The 66-year-old will be the first woman and the first African to occupy the position.
Despite recently taking out US citizenship, she revels in being Nigerian and is fiercely patriotic – flaunting her African identity in her African-print tailored outfits.
She told the BBC in 2012 that she had in fact adopted such attire as a working mother of four to do the school run, an easy answer for a smart look – and a thrifty one at that, given she estimated each outfit cost around $25.
The Harvard-educated development economist is seen as a down-to-earth, hard worker, who told BBC HardTalk in July that what the WTO needed was a shake-up.
“They need something different, it cannot be business as usual for the WTO – [they need] someone willing to do the reforms and lead.”
Reform in Nigeria
During her 25 years at the World Bank, she is credited with spearheading several initiatives to assist low-income countries, in particular raising nearly $50bn in 2010 from donors for the International Development Association (IDA), the World Bank’s fund for the poorest countries.
But it is her reform agenda in Nigeria in which she takes real pride – especially the two times she served as the country’s finance minister under Presidents Olusegun Obasanjo and Goodluck Jonathan.
One of her greatest achievements was leading a team which negotiated a whopping $18bn debt right-off in 2005 for the country, helping Nigeria obtain its first ever sovereign debt rating.
The country’s debts had dated back to the early 1980s, and had ballooned to more than $35bn due to penalties and late fees during the 1990s.
Her economic reforms had a far-reaching impact and saved Nigeria at a critical period, according to prominent Nigerian economist, Bismarck Rewane.
This included de-linking the budget from the oil price, allowing the country to save money in a special account when oil prices were high.
“It was this buffer that ensured Nigeria’s economy survived between 2008 and 2009,” Mr Rewane told the BBC.
Ms Okonjo-Iweala had given up a well-paid job at the World Bank and left her family in Washington, where her husband works as a neurosurgeon, to work in Nigeria, where unlike other ministers she did not have a large domestic staff or fleet of cars.
In fact she even liked doing her own cooking when she could, with cowtail pepper soup being a favourite, a Financial Times interview revealed in 2015.
But her reforms and especially her crackdown on corruption in the fuel sector, where some powerful importers – known as marketers – claimed huge sums of money in subsidies from the government for fuel they had not sold, came at personal cost.
Her mother, Kamene Okonjo – a medical doctor and retired professor of sociology – was kidnapped from her home in southern Nigeria in 2012, aged 82.
Kidnapping is common in Nigeria, where it is a lucrative criminal enterprise and families often pay up as the security services do not often find those abducted.
The then-finance minister said the kidnappers had first demanded her resignation and then a ransom.
ut she says she refused to do either.
“I knew that the largest vested interest that I had recently offended in my anti-corruption work was an unscrupulous subset of the country’s oil marketers,” she said in her account of the event.
Mrs Okonjo was released within five days in unclear circumstances, but her daughter’s no-nonsense approach may have come to bear in the matter.
One of her sons – Uzodinma Iweala, author of the 2005 novel Beast of No Nation – has said of his strict upbringing: “My mum is a very powerful woman. She knows how she wants things done, and if you don’t it her way, you are in trouble.”
Born 1954 in Nigeria
Studied at Harvard 1973-76 and earned a PhD at Massachusetts Institute of Technology (MIT) in 1981
Spent 25 years at the World Bank, rising to the No.2 position as managing director (2007-11)
Twice Nigerian finance minister – 2003-2006 and 2011-2015 – and the first woman to hold the post
Served briefly as foreign minister in 2006, also the first woman to do so
Sits on the boards of Twitter, Standard Chartered Bank and the Global Alliance for Vaccines and Immunization (GAVI)
Nominated by President Mohammadu Buhari as candidate for director-general of the WTO in June 2020.